Journal of Medical Virology
Volume 46, Issue 1, 1995, Pages 61-65

Prevalence of antibodies against hepatitis A virus among new immigrants in Israel (Article)

Karetnyi Y.V. , Mendelson E.* , Shlyakhov E. , Rubinstein E. , Golubev N. , Levin R. , Sandler M. , Schreiber M. , Rubinstein U. , Shif I. , Handsher R. , Varsano N. , Modan B.
  • a Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • b Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • c Unit of Infectious Diseases, Chaim Sheba Medical Center, Laniado Hospital, Tel‐Hashomer, Netanya, Israel
  • d Unit of Infectious Diseases, Chaim Sheba Medical Center, Laniado Hospital, Tel‐Hashomer, Netanya, Israel
  • e Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • f Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • g Tel-Auiu University Sackler School of Medicine, Subdistrict Health Department Netanya, Laniado Hospital, Netanya, Israel
  • h Department of Pediatrics, Laniado Hospital, Netanya, Israel
  • i Department of Pediatrics, Laniado Hospital, Netanya, Israel
  • j Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • k Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • l Central Virology Laboratory Public Health Services, Chaim Sheba Medical Center, Tel-Hashomer, Israel, Laniado Hospital, Netanya, Israel
  • m Department of Epidemiology, Chaim Sheba Medical Center, Laniado Hospital, Tel‐Hashomer, Netanya, Israel

Abstract

Israel, located in a region endemic for hepatitis A virus (HAW, recently absorbed a large popula tion of immigrants who came from the former USSR. To assess the risk of high morbidity in this population a serosurvey of HAV antibodies was undertaken. Serum samples were collected from 965 new immigrants, of whom 664 came from the European, non‐endemic region, and 301 from the Asian and Caucasian endemic regions of the former Soviet Union. They were compared to 240 Israelis. Each population was divided into six age groups: 1‐9, 10‐′l9, 20‐29, 30‐39, 40‐49, and 50 years of age and older. The Asian/Caucasian immigrants and the Israeli population were found to share similar characteristics. In both groups, antibodies to HAV (anti‐HAV) were present in the 1‐9‐year‐old age group and reached maximum prevalence (90% and 86.7%, respectively) in the 20‐29‐year‐old age group. In contrast, among the European immigrants anti‐HAV was first found in the 10‐19‐year‐olds and peaked (93%) in the age group of 50 years and older. It is concluded that immigrants originating from the European part of the former USSR may require vaccination against hepatitis A. © 1995 Wiley‐Liss, Inc. Copyright © 1995 Wiley‐Liss, Inc., A Wiley Company

Author Keywords

risk of morbidity Serosurvey Seroprevalence

Index Keywords

immigrant Hepatitis A Antibodies Israel risk human risk assessment hepatitis A controlled study USSR antibody detection Adolescent male female Infant Child, Preschool prevalence Article infection control Support, Non-U.S. Gov't adult major clinical study hepatitis a virus Emigration and Immigration Hepatovirus vaccination Seroepidemiologic Studies hepatitis A vaccine Hepatitis Antibodies Middle Age Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028970223&doi=10.1002%2fjmv.1890460114&partnerID=40&md5=0bd981c5674f4530805689b43ea75497
DOI: 10.1002/jmv.1890460114
ISSN: 01466615
Cited by: 9
Original Language: English