Journal of Medical Virology
Volume 43, Issue 4, 1994, Pages 412-414

Hepatitis E—An important cause of imported non‐A, non‐B hepatitis among migrant workers in Qatar (Article)

Shidrawi R.G.* , Skidmore S.J. , Coleman J.C. , Dayton R. , Murray‐Lyon I.M.
  • a Charing Cross Hospital, London, United Kingdom
  • b Regional Virus Laboratory, Birmingham Heartlands Hospital, Birmingham, United Kingdom
  • c Charing Cross Hospital, London, United Kingdom
  • d Charing Cross Hospital, London, United Kingdom
  • e Charing Cross Hospital, London, United Kingdom

Abstract

In 1985, Glynn et al. [Journal of Medical Virology 17:371–375] reported on epidemic viral hepatitis in Qatar and concluded that 72% (91/126) had acute enteric ally transmitted non‐A, non‐B viral hepatitis (ET‐NANBH). Most of the patients (98%) presented within 8 weeks of arrival in Qatar and were migrant workers from the Indian subcontinent. The data was reanalyzeda for evidence of infection with hepatitis E virus (HEV). Seventy‐eight of 91 (86%) of stored sera were still suitable for analysis since collection in 1981. A newly described enzyme immunoassay (EIA) for both IgG and IgM anti‐HEV was used (Abbott Laboratories, Delkenheim, Germany); 59/78 (76%) were positive for either or both assays. All but two were from the Indian subcontinent. The data suggest that HEV was the major cause of ET‐NANBH in Qatar in 1981, particularly among newly arrived migrant workers from the Indian subcontinent. © 1994 Wiley‐Liss, Inc. Copyright © 1994 Wiley‐Liss, Inc., A Wiley Company

Author Keywords

assays for anti‐HEV HEV ELISA Viral hepatitis

Index Keywords

India human Qatar Cohort Studies controlled study Asia, Western Seasons migrant worker male female enzyme linked immunosorbent assay Disease Outbreaks Article major clinical study adult Sex Factors Age Factors hepatitis virus Non-A, non-B hepatitis virus hepatitis non a non b non a non b hepatitis virus Immunoenzyme Techniques Enzyme-Linked Immunosorbent Assay Transients and Migrants immunoglobulin G Hepatitis E virus Hepatitis E immunoglobulin M Hepatitis Antibodies
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027979017&doi=10.1002%2fjmv.1890430416&partnerID=40&md5=3d470a411044f0c905180bc29ddc7987
DOI: 10.1002/jmv.1890430416
ISSN: 01466615
Cited by: 11
Original Language: English