Italian Journal of Pediatrics
Volume 44, Issue 1, 2018

Epidemiology and risk factors of hypovitaminosis D in a cohort of internationally adopted children: A retrospective study (Article) (Open Access)

Salerno G. , Ceccarelli M. , De Waure C. , D'Andrea M. , Buonsenso D. , Faccia V. , Pata D. , Valentini P.*
  • a Department of Woman and Child Health, A. Gemelli University Hospital Foundation, Unit of Pediatrics, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, Rome, 00168, Italy
  • b Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, Via Consolare Valeria, 1, Messina, 98125, Italy
  • c Public Health Institute, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, Rome, 00168, Italy
  • d Public Health Institute, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, Rome, 00168, Italy
  • e Department of Woman and Child Health, A. Gemelli University Hospital Foundation, Unit of Pediatrics, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, Rome, 00168, Italy
  • f Department of Gynecologic, Pediatric and Neonatologic Sciences, Sant'Andrea University Hospital, Unit of Pediatrics, University Sapienza of Rome, Rome, Italy
  • g Department of Woman and Child Health, A. Gemelli University Hospital Foundation, Unit of Pediatrics, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, Rome, 00168, Italy
  • h Department of Woman and Child Health, A. Gemelli University Hospital Foundation, Unit of Pediatrics, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, Rome, 00168, Italy

Abstract

Background: Predictors of hypovitaminosis D were extensively studied in the adult population, leading to an approximately complete understanding of them, while there is a lack of studies in the pediatric population, especially in migrant and internationally adopted children. In this retrospective study, we tried to identify the major laboratory predictors of hypovitaminosis D in a cohort of internationally adopted children. Methods: Data were extracted from the database of the "Ethnopediatrics Outpatient Clinic" of the "A. Gemelli" Foundation University Hospital in Rome, Italy. Our study included 873 children evaluated from March 2007 to May 2016. Analysis of variance, chi square test, t test and multivariate logistic regression were performed, a "p" value < 0.05 was considered significant, with a confidence interval of 95%. Results: We did not find any significant correlation between Vitamin D and Calcium, Phosphates or Magnesium levels within the population we examined. Moreover, parathyroid hormone is not a good predictor of Vitamin D Status. Conclusions: Considering the strong influence Vitamin D status has not only on bone health, but also on general well-being, it is due to perform a vitamin D assessment as soon as possible, especially in internationally adopted children. © 2018 The Author(s).

Author Keywords

Internationally adopted children Rickets Vitamin D deficiency Parathormone

Index Keywords

human sex difference statistics and numerical data Calcium Phosphates phosphate alkaline phosphatase blood level magnesium rickets phosphate blood level alkaline phosphatase skin color Humans adopted child parathyroid hormone post hoc analysis calcium blood level 25 hydroxyvitamin D male Child, Adopted preschool child female Infant risk factor geographic origin Risk Factors Child, Preschool prevalence seasonal variation vitamin D deficiency Article Retrospective Studies blood major clinical study Social Environment age Italy disease severity retrospective study Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050738862&doi=10.1186%2fs13052-018-0527-4&partnerID=40&md5=e1885bd972f6cc9b6a73ab982f74fc0a
DOI: 10.1186/s13052-018-0527-4
ISSN: 17208424
Cited by: 1
Original Language: English