Clinical Infectious Diseases
Volume 15, Issue 6, 1992, Pages 924-937

Cutaneous leishmaniasis: Review of 59 cases seen at the national institutes of health (Article)

Melby P.C. , Kreutzer R.D. , McMahon-Pratt D. , Gam A.A. , Neva F.A.*
  • a Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States, Biology Department, Youngstown State University, Youngstown, OH, United States, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, United States, Division of Infectious Diseases, Department of Medicine, The University of Texas Health Sciences Center at San Antonio, San Antonio, TX, United States
  • b Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States, Biology Department, Youngstown State University, Youngstown, OH, United States, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, United States
  • c Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States, Biology Department, Youngstown State University, Youngstown, OH, United States, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, United States
  • d Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States, Biology Department, Youngstown State University, Youngstown, OH, United States, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, United States
  • e Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States, Biology Department, Youngstown State University, Youngstown, OH, United States, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, United States

Abstract

Fifty-nine cases of cutaneous leishmaniasis seen at the National Institutes of Health in Bethesda, Maryland, are reviewed. The group of patients involved was unique in that the majority were American civilians, their disease was acquired in many different endemic areas of the world, and their illnesses represented all points on the clinical spectrum of cutaneous disease. The majority of American patients acquired leishmaniasis while engaging in activities related to their occupations. Cutaneous disease acquired in the New World usually consisted of one or two lesions, while multiple lesions often characterized Old World infections with Leishmania major. Patients with chronic relapsing or diffuse cutaneous leishmaniasis were native to endemic areas and were infected at an early age. Even the localized form of cutaneous leishmaniasis was often extensive and difficult to treat. Diagnosis with culture and identification of the parasite to the subspecies level is instrumental in the selection of optimal therapy. Cutaneous leishmaniasis may be encountered increasingly often in the United States because of the frequent international travel of U.S. residents and the influx of immigrants from endemic areas of the world. © 1992 Oxford University Press.

Author Keywords

[No Keywords available]

Index Keywords

Leishmaniasis, Cutaneous parasite identification clinical feature human arthralgia priority journal arthritis United States Leishmania major liver toxicity anemia Adolescent male female occupational exposure Child, Preschool stibogluconate sodium Review National Institutes of Health (U.S.) parasite cultivation nephrotoxicity amphotericin b hyperthermic therapy ketoconazole bone marrow toxicity major clinical study adult endemic disease histopathology skin leishmaniasis Fatigue Middle Age Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026526268&doi=10.1093%2fclind%2f15.6.924&partnerID=40&md5=288512e09bd4e858b10fca2cdd6b63e5
DOI: 10.1093/clind/15.6.924
ISSN: 10584838
Cited by: 72
Original Language: English