Acta Neurologica Scandinavica
Volume 85, Issue 6, 1992, Pages 408-411

Migration and age at onset of multiple sclerosis: some pitfalls of migrant studies (Article)

Delasnerie‐Lauprêtre N.* , Alpérovitch A.
  • a French Collaborative Group on Multiple Sclerosis, INSRM, Villejuif, France
  • b French Collaborative Group on Multiple Sclerosis, INSRM, Villejuif, France

Abstract

The aim of this study was to compare age at onset of multiple sclerosis (MS) in North African‐born and French‐born patients. The migrant group consisted of 246 patients who arrived in France during the period 1960–1965. Among these migrants, 27 (11%) had first symptoms before migration. The French‐born group consisted of MS patients of same sex and age at the time of the study as migrants who were randomly selected from a large national sample. After controlling for various biases which could explain differences between migrants and French‐born patients, we found no differences in mean age at MS onset between the two groups. Therefore, it is likely that MS was acquired by the same age in migrants as in French‐born patients. This finding may constitute an indirect support for the hypothesis that the unknown causative factors of MS are equally frequent whatever the latitude of origin. Copyright © 1992, Wiley Blackwell. All rights reserved

Author Keywords

age at onset multiple sclerosis Migrants

Index Keywords

male priority journal female major clinical study Risk Factors Emigration and Immigration multiple sclerosis Incidence Africa, Northern Article France Cross-Sectional Studies human adult Middle Age migration age

Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026695243&doi=10.1111%2fj.1600-0404.1992.tb06038.x&partnerID=40&md5=dbb1e3b24c64aef40e67dfba59ed3fef

DOI: 10.1111/j.1600-0404.1992.tb06038.x
ISSN: 00016314
Cited by: 14
Original Language: English