Tropical Medicine and International Health
Volume 3, Issue 12, 1998, Pages 975-980

Outcome of second-line tuberculosis treatment in migrants from vietnam: International organization for migration (IOM) tuberculosis working group (Article)

Bollini P.* , Pampallona S. , O'Rourke T. , Jones W. , Truong T.B. , Nguyen H.P. , Bang L.C. , An D.Q. , Keane V.P. , Siem H. , Gushulak B.
  • a ForMed, Evolène, Switzerland, ForMed, 1983 Evolène, Switzerland
  • b ForMed, Evolène, Switzerland
  • c IOM, Ho-Chi-Minh City, Viet Nam
  • d IOM, Ho-Chi-Minh City, Viet Nam
  • e IOM, Ho-Chi-Minh City, Viet Nam
  • f IOM, Ho-Chi-Minh City, Viet Nam
  • g 30Th April Hospital, Ho-Chi-Minh City, Viet Nam
  • h Cho Ray Hospital, Ho-Chi-Minh City, Viet Nam
  • i IOM, Harare, Zimbabwe
  • j IOM, Genva, Switzerland
  • k IOM, Genva, Switzerland

Abstract

From 1990 to 1995, 410 441 prospective migrants were screened for tuberculosis (TB) in Ho-Chi-Minh City (Vietnam), within the framework of the Orderly Departure Programme. 161 individuals had multidrug-resistant (MDR) TB and were treated with a seven-drug regimen (isoniazid, rifampicin, ethambutol, pyrazinamide, capreomycin, cycloserine, and ethionamide) for at least 12 months. In January 1996, 31 of these patients were still on treatment. The cumulative percentage of cure was 21% at 18 months, 71.6% at 36 months, and 81.2% at 55 months. Sex, age, presence of cavities, and previous tuberculosis treatment did not affect the chance of cure, but age > 45 years significantly affected the chance of treatment failure (nonadherence, death, treatment stopped due to side effects).

Author Keywords

Immigrants and emigrants Vietnam tuberculosis

Index Keywords

Vietnam immigrant mass screening capreomycin human middle aged Tuberculosis, Multidrug-Resistant Humans ofloxacin Treatment Outcome Antitubercular Agents male tuberculostatic agent female Viet Nam tuberculosis cycloserine Article streptomycin patient compliance multidrug resistance adult major clinical study isoniazid rifabutin Emigration and Immigration ethambutol ethionamide rifampicin pyrazinamide
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032432837&partnerID=40&md5=8b7f6ef80553c7ffaf616a217aef22a3
ISSN: 13602276
Cited by: 6
Original Language: English