Immunologist
Volume 5, Issue 1, 1997, Pages 21-26

Pathogenesis of AIDS in Africa - Lessons from the Ethiopian immigrants in Israel (Article)

Bentwich Z.* , Weisman Z. , Grossman Z. , Galai N. , Kalinkovich A.
  • a AIDS Center, Ruth Ben-Ari Clinic. Immunol. Inst., Hebrew University Medical School, Rehovot, 76100, Israel
  • b AIDS Center, Ruth Ben-Ari Clinic. Immunol. Inst., Hebrew University Medical School, Rehovot, 76100, Israel
  • c AIDS Center, Ruth Ben-Ari Clinic. Immunol. Inst., Hebrew University Medical School, Rehovot, 76100, Israel
  • d AIDS Center, Ruth Ben-Ari Clinic. Immunol. Inst., Hebrew University Medical School, Rehovot, 76100, Israel
  • e AIDS Center, Ruth Ben-Ari Clinic. Immunol. Inst., Hebrew University Medical School, Rehovot, 76100, Israel

Abstract

The AIDS epidemic in Africa differs from that seen in North America and Europe. Based in part on results obtained from a unique natural 'experiment' involving the immigration of Ethiopians to Israel, Zvi Bentwich and colleagues suggest here that chronic parasite infection, leading to persistent immune stimulation of individuals in Africa, rather than the prevalent HIV-1 subtype, may account for the increased rate of progression of the disease there.

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Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030904375&partnerID=40&md5=13da9bf48058cdeaaf8eea39d398d590
ISSN: 11925612
Cited by: 29
Original Language: English