European Journal of Gastroenterology and Hepatology
Volume 9, Issue 2, 1997, Pages 191-194

Helicobacter pylori infection and upper gastrointestinal pathology in a British immigrant Indian community (Article)

Seery J.P. , Henshaw D.J. , Sandhu P.J. , Mather H.M. , Ahmad F. , McNeil I. , Arnold J.D.*
  • a Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom
  • b Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom
  • c Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom
  • d Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom
  • e Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom
  • f Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom
  • g Department of Medicine, Ealing Hospital NHS Trust, Middlesex, United Kingdom, Department of Medicine, Ealing Hospital NHS Trust, Uxbridge Road, Middlesex UB1 3HW, United Kingdom

Abstract

Objectives: To assess the pattern of upper gastrointestinal pathology and the prevalence of Helicobacter pylori infection in the Southall Indian community. Design: A prospective study of endoscopic findings in 124 Indian and 107 whites from the Southall area. In a separate study blood samples were taken from 100 Indian subjects presenting to a single general practitioner in Southall. Methods: The presence of gastritis and H. pylori infection was assessed histologically in Indian and white patients undergoing endoscopy. Serum samples were analysed using a specific enzyme-linked immunosorbent assay (ELISA) for anti-H. pylori immunoglobulin G. Results: In the endoscopic study, Indian and white patients had the same rate of H. pylori infection (52% vs. 43%, respectively) (P = NS). The pattern of upper gastrointestinal pathology was similar in whites and Indians. In the general practice based study 41 subjects were H. pylori seropositive. Seropositivity increased with age (P < 0.05). Conclusion: There is no excess of H. pylori-related pathology in Southall immigrant Indians. The similarity of upper gastrointestinal pathology in UK Indian acid white patients presenting for endoscopy suggests that the high rates of duodenal ulceration, gastritis and H. pylori infection in India are environmentally rather than racially determined.

Author Keywords

immigrants Seroprevalence peptic ulcer Gastritis Helicobacter pylori Indian

Index Keywords

prospective study immigrant Indian human priority journal pathology Aged duodenum ulcer gastrointestinal infection male female enzyme linked immunosorbent assay prevalence Article major clinical study adult Gram negative infection Helicobacter pylori gastritis bacterium antibody immunoglobulin G
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031054532&doi=10.1097%2f00042737-199702000-00016&partnerID=40&md5=2e949d2ce3cf2cf2bcebd617b82a12be
DOI: 10.1097/00042737-199702000-00016
ISSN: 0954691X
Cited by: 6
Original Language: English