Posttraumatic stress disorder as a significant correlate of voluntary antiretroviral treatment interruption in adult HIV-infected patients followed up in French hospitals: Data from the ANRS-VESPA2 national survey

Journal of Clinical Psychiatry
Volume 79, Issue 3, 2018

Posttraumatic stress disorder as a significant correlate of voluntary antiretroviral treatment interruption in adult HIV-infected patients followed up in French hospitals: Data from the ANRS-VESPA2 national survey (Article)

Roux P.* , Marcellin F. , Ndiaye K. , Suzan-Monti M. , Mayet A. , Duracinsky M. , Briand-Madrid L. , Maradan G. , Mora M. , Préau M. , Verger P. , Carrieri P. , Dray-Spira R. , Spire B. , Lert F. , Carrieri M.P. , Hamelin C. , Lorente N. , Le Strat Y. , Cuzin L. , Meyer L. , Rojas-Castro D. , Fischer H. , Fradier Y. , Allegre T. , Mours P. , Riou J.M. , Sordage M. , Chennebault J.M. , Fialaire P. , Rabier V. , Froidure M. , Huguet D. , Leduc D. , Pichancourt G. , Wajsbrot A. , Bourdeaux C. , Foltzer A. , Hoen B. , Hustache-Mathieu L. , Abgrall S. , Barruet R. , Bouchaud O. , Chabrol A. , Mattioni S. , Mechai F. , Jeantils V. , Bernard N. , Bonnet F. , Hessamfar M. , Lacoste D. , Malvy D. , Mercie P. , Morlat P. , Paccalin F. , Pertusa M.C. , Pistone T. , Receveur M.C. , Vandenhende M.A. , Dupont C. , Freire Maresca A. , Leporrier J. , Rouveix E. , Dargere S. , De La Blanchardiere A. , Martin A. , Noyon V. , Verdon R. , Rogeaux O. , Beytout J. , Gourdon F. , Laurichesse H. , Meier F. , Mortier E. , Simonpoli A.M. , Cordier F. , Delacroix I. , Garrait V. , Elharrar B. , Dominguez S. , Lascaux A.S. , Lelievre J.D. , Levy Y. , Melica G. , Buisson M. , Piroth L. , Waldner A. , Gruat N. , Lepretre A. , De Truchis P. , Le Du D. , Melchior J.Cl. , Sehouane R. , Troisvallets D. , Blanc M. , Boccon-Gibod I. , Bosseray A. , Brion J.P. , Durand F. , Leclercq P. , Marion F. , Pavese P. , Brottier-Mancini E. , Faba L. , Roncato-Saberan M. , Bollengier-Stragier O. , Esnault J.L. , Leautez-Nainville S. , Perre P. , Froguel E. , Nguessan M. , Simon P. , Colardelle P. , Doll J. , Godin-Collet C. , Roussin-Bretagne S. , Delfraissy J.F. , Goujard C. , Peretti D. , Quertainmont Y. , Marionneau J. , Aissi E. , Van Grunderbeeck N. , Denes E. , Ducroix-Roubertou S. , Genet C. , Weinbreck P. , Augustin-Normand C. , Boibieux A. , Cotte L. , Ferry T. , Koffi J. , Miailhes P. , Perpoint T. , Peyramond D. , Schlienger I. , Brunel J.M. , Carbonnel E. , Chiarello P. , Livrozet J.M. , Makhloufi D. , Dhiver C. , Husson H. , Madrid A. , Ravaux I. , De Severac M.L. , Thierry Mieg M. , Tomei C. , Hakoun S. , Moreau J. , Mokhtari S. , Soavi M.J. , Faucher O. , Menard A. , Orticoni M. , Poizot-Martin I. , Atoui N. , Baillat V. , Faucherre V. , Favier C. , Jacquet J.M. , Le Moing V. , Makinson A. , Mansouri R. , Merle C. , Elforzli N. , Allavena C. , Aubry O. , Besnier M. , Billaud E. , Bonnet B. , Bouchez S. , Boutoille D. , Brunet C. , Feuillebois N. , Lefebvre M. , Morineau-Le Houssine P. , Mounoury O. , Point P. , Raffi F. , Reliquet V. , Talarmin J.P. , Ceppi C. , Cua E. , Dellamonica P. , De Salvador-Guillouet F. , Durant J. , Ferrando S. , Mondain-Miton V. , Perbost I. , Pillet S. , Prouvost-Keller B. , Pradier C. , Pugliese P. , Rahelinirina V. , Roger P.M. , Rosenthal E. , Sanderson F. , Hocqueloux L. , Niang M. , Prazuck T. , Arsac P. , Barrault-Anstett M.F. , Ahouanto M. , Bouvet E. , Castanedo G. , Charlois-Ou C. , Dia Kotuba A. , Eid-Antoun Z. , Jestin C. , Jidar K. , Joly V. , Khuong-Josses M.A. , Landgraf N. , Landman R. , Lariven S. , L'Heriteau F. , Machado M. , Matheron S. , Michard F. , Morau G. , Pahlavan G. , Phung B.C. , Prevot M.H. , Rioux C. , Yeni P. , Bani-Sadr F. , Calboreanu A. , Chakvetadze E. , Salmon D. , Silbermann B. , Batisse D. , Beumont M. , Castiel P. , Derouineau J. , Eliaszewicz M. , Gonzalez G. , Jayle D. , Karmochkine M. , Kousignian P. , Pavie J. , Pierre I. , Weiss L. , Badsi E. , Bendenoun M. , Cervoni J. , Diemer M. , Durel A. , Rami A. , Sellier P. , Ait-Mohand H. , Amirat N. , Bonmarchand M. , Bourdillon F. , Breton G. , Caby F. , Grivois J.P. , Katlama C. , Kirstetter M. , Paris L. , Pichon F. , Roudiere L. , Schneider L. , Samba M.C. , Seang S. , Simon A. , Stitou H. , Tubiana R. , Valantin M.A. , Bollens D. , Bottero J. , Bui E. , Campa P. , Fonquernie L. , Fournier S. , Girard P.M. , Goetschel A. , Guyon H.F. , Lacombe K. , Lallemand F. , Lefebvre B. , Maynard J.L. , Meyohas M.C. , Ouazene Z. , Pacanowski J. , Picard O. , Raguin G. , Roussard P. , Tourneur M. , Tredup J. , Valin N. , Balkan S. , Clavel F. , Colin De Verdiere N. , De Castro N. , De Lastours V. , Ferret S. , Gallien S. , Gerard L. , Goguel J. , Lafaurie M. , Lascoux-Combe C. , Molina J.M. , Oksenhendler E. , Pintado C. , Ponscarme D. , Rozenbaum W. , Scemla A. , Bonnard P. , Lassel L. , Lebrette M.G. , Lyavanc T. , Mariot P. , Missonnier R. , Ohayon M. , Pialoux G. , Treilhou M.P. , Vincensini J.P. , Gilquin J. , Hadacek B. , Nait-Ighil L. , Nguyen T.H. , Sobel A. , Viard J.P. , Zak Dit Zbar O. , Aumaitre H. , Eden A. , Ferreyra M. , Lopez F. , Medus M. , Neuville S. , Saada M. , Blum L. , Perfezou P. , Arvieux C. , Chapplain J.M. , Revest M. , Souala F. , Tattevin P. , Bord S. , Borsa-Lebas F. , Caron F. , Chapuzet C. , Debab Y. , Gueit I. , Etienne M. , Fartoukh C. , Feltgen K. , Joly C. , Robaday-Voisin S. , Suel P. , Khuong M.A. , Krausse J. , Poupard M. , Tran Van G. , Cazorla C. , Daoud F. , Fascia P. , Fresard A. , Guglielminotti C. , Lucht F. , Bernard-Henry C. , Cheneau C. , Lang J.M. , De Mautort E. , Partisani M. , Priester M. , Rey D. , Majerholc C. , Zucman D. , Assi A. , Lafeuillade A. , De Jaureguiberry J.P. , Gisserot O. , Aquilina C. , Prevoteau Du Clary F. , Alvarez M. , Chauveau M. , Delobel P. , Garipuy D. , Labau E. , Marchou B. , Massip P. , Mularczyk M. , Obadia M. , Ajana F. , Allienne C. , Baclet V. , De La Tribonniere X. , Huleux T. , Melliez H. , Meybeck A. , Riff B. , Valette M. , Viget N. , Bastides F. , Bernard L. , Gras G. , Guadagnin P. , May T. , Rabaud C. , Dos Santos A. , Poinsignon Y. , Derradji O. , Escaut L. , Teicher E. , Vittecoq D. , Bantsima J. , Caraux-Paz P. , Patey O. , ANRS-VESPA2 Study Group

^a Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France
^b Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France, INSERM UMR912, France
^c Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France
^d Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France, GReSP Lyon 2, France
^e Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, Centre d'Épidémiologie et de Santé Publique des Armées, Marseille, France
^f EA 7334 REMES, Patient-Centered Outcomes Research, Sorbonne Paris Cité, Paris-Diderot University, Paris, France, URC-ECO, Hôpital Hôtel-Dieu, AP-HP, Paris, France, Service de Médecine Interne et d'Immunologie Clinique, Hôpital Bicêtre, AP-HP, Kremlin-Bicêtre, France, INSERM UMR912, France; Hopital de Bicetre, Le Kremlin-Bicetre, France
^g Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France
^h Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France
ⁱ Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France, EA 7334 REMES, France
^j Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, Groupe de Recherche en Psychologie Sociale, Université Lyon 2, Lyon, France, CEEISCAT, France
^k Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France
^l Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France
^m INSERM, UMR-S1136, Pierre Louis Institute of Epidemiology and Public Health, Team Research in Social Epidemiology, Paris, France, Sorbonne Universités, UPMC Univ Paris 06, UMR-S1136, Pierre Louis Institute of Epidemiology and Public Health, Team Research in Social Epidemiology, Paris, France, INSERM UMR912, France
ⁿ Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques and Sociales de la Santé and Traitement de l'Information Médicale, 19-21 Blvd Jean Moulin, Marseille, 13005, France, ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France, INSERM UMR912, France
^o INSERM UMR-S1136, France
^p INSERM UMR912, France
^q INSERM UMR-S1136, France
^r INSERM U687, France
^s InVS, Saint-Maurice, France
^t Hopital Purpan, Toulouse, France; Hopital Purpan, France
^u CESP, INSERM, Le Kremlin Bicetre, France
^v Aides, Pantin, France
^w Act-Up Paris, France
^x Ipsos, Paris, France
^y CH Pays d'Aix, Aix-en-Provence, France
^z CH Pays d'Aix, Aix-en-Provence, France
^a CH Pays d'Aix, Aix-en-Provence, France
^b CH Pays d'Aix, Aix-en-Provence, France
^c CHU Hotel-Dieu, Angers, France
^d CHU Hotel-Dieu, Angers, France
^e CHU Hotel-Dieu, Angers, France
^f CH Alpes-Leman, Annemasse, France
^g CH Alpes-Leman, Annemasse, France
^h CH Alpes-Leman, Annemasse, France
ⁱ Hopital Henri Duffaut, Avignon, France
^j Hopital Henri Duffaut, Avignon, France
^k Hopital Saint-Jacques, Besancon, France
^l Hopital Saint-Jacques, Besancon, France
^m Hopital Saint-Jacques, Besancon, France
ⁿ Hopital Saint-Jacques, Besancon, France
^o Hopital Avicenne, Bobigny, France
^p Hopital Avicenne, Bobigny, France
^q Hopital Avicenne, Bobigny, France
^r Hopital Avicenne, Bobigny, France
^s Hopital Avicenne, Bobigny, France
^t Hopital Avicenne, Bobigny, France
^u Hopital Jean Verdier, Bondy, France
^v Hopital Saint-Andre, Bordeaux, France
^w Hopital Saint-Andre, Bordeaux, France
^x Hopital Saint-Andre, Bordeaux, France
^y Hopital Saint-Andre, Bordeaux, France
^z Hopital Saint-Andre, Bordeaux, France
^a Hopital Saint-Andre, Bordeaux, France
^b Hopital Saint-Andre, Bordeaux, France
^c Hopital Saint-Andre, Bordeaux, France
^d Hopital Saint-Andre, Bordeaux, France
^e Hopital Saint-Andre, Bordeaux, France
^f Hopital Saint-Andre, Bordeaux, France
^g Hopital Saint-Andre, Bordeaux, France
^h Hopital Ambroise Pare, Boulogne-Billancourt, France
ⁱ Hopital Ambroise Pare, Boulogne-Billancourt, France
^j Hopital Ambroise Pare, Boulogne-Billancourt, France
^k Hopital Ambroise Pare, Boulogne-Billancourt, France
^l Hopital Clemenceau, Caen, France
^m Hopital Clemenceau, Caen, France
ⁿ Hopital Clemenceau, Caen, France
^o Hopital Clemenceau, Caen, France
^p Hopital Clemenceau, Caen, France
^q CH de Chambery, France
^r CHU Gabriel Montpied, Clermont-Ferrand, France
^s CHU Gabriel Montpied, Clermont-Ferrand, France
^t CHU Gabriel Montpied, Clermont-Ferrand, France
^u Hopital Louis-Mourier, Colombes, France
^v Hopital Louis-Mourier, Colombes, France
^w Hopital Louis-Mourier, Colombes, France
^x CH Laennec, Creil, France
^y CHIC, Creteil, France
^z CHIC, Creteil, France; Hopital Saint-Louis, France
^a CHIC, Creteil, France
^b Hopital Henri Mondor, France
^c Hopital Henri Mondor, France
^d Hopital Henri Mondor, France
^e Hopital Henri Mondor, France
^f Hopital Henri Mondor, France
^g Hopital du Bocage, Dijon, France; Hopital Europeen Georges-Pompidou, France
^h Hopital du Bocage, Dijon, France
ⁱ Hopital du Bocage, Dijon, France
^j Hopital Simone Veil, Eaubonne, France
^k Hopital Simone Veil, Eaubonne, France; Hopital Bichat - Claude-Bernard, Paris, France
^l Hopital Raymond-Poincare, Garches, France
^m Hopital Raymond-Poincare, Garches, France
ⁿ Hopital Raymond-Poincare, Garches, France
^o CH de Gonesse, France
^p CH de Gonesse, France
^q CHU de Grenoble, France
^r CHU de Grenoble, France
^s CHU de Grenoble, France
^t CHU de Grenoble, France
^u CHU de Grenoble, France
^v CHU de Grenoble, France
^w CHU de Grenoble, France
^x CHU de Grenoble, France
^y Hopital Saint-Louis, La Rochelle, France
^z Hopital Saint-Louis, La Rochelle, France
^a Hopital Saint-Louis, La Rochelle, France
^b CHD les Oudairies, La Rochesur-Yon, France
^c CHD les Oudairies, La Rochesur-Yon, France
^d CHD les Oudairies, La Rochesur-Yon, France
^e CHD les Oudairies, La Rochesur-Yon, France
^f CH de Lagny Marne-la-Vallee, France
^g CH de Lagny Marne-la-Vallee, France
^h CH de Lagny Marne-la-Vallee, France
ⁱ CH de Versailles, Le Chesnay, France
^j CH de Versailles, Le Chesnay, France
^k CH de Versailles, Le Chesnay, France
^l CH de Versailles, Le Chesnay, France
^m Hopital de Bicetre, Le Kremlin-Bicetre, France
ⁿ Hopital de Bicetre, Le Kremlin-Bicetre, France
^o Hopital de Bicetre, Le Kremlin-Bicetre, France
^p Hopital de Bicetre, Le Kremlin-Bicetre, France
^q CH du Mans, France
^r CH Dr Schaffner, Lens, France
^s CH Dr Schaffner, Lens, France
^t CHU Dupuytren, Limoges, France
^u CHU Dupuytren, Limoges, France
^v CHU Dupuytren, Limoges, France
^w CHU Dupuytren, Limoges, France
^x Hopital de la Croix-Rousse, Lyon, France
^y Hopital de la Croix-Rousse, Lyon, France
^z Hopital de la Croix-Rousse, Lyon, France
^a Hopital de la Croix-Rousse, Lyon, France
^b Hopital de la Croix-Rousse, Lyon, France
^c Hopital de la Croix-Rousse, Lyon, France
^d Hopital de la Croix-Rousse, Lyon, France
^e Hopital de la Croix-Rousse, Lyon, France
^f Hopital de la Croix-Rousse, Lyon, France
^g Hopital Edouard-Herriot, France
^h Hopital Edouard-Herriot, France
ⁱ Hopital Edouard-Herriot, France
^j Hopital Edouard-Herriot, France
^k Hopital Edouard-Herriot, France
^l Hopital de la Conception, Marseille, France
^m Hopital de la Conception, Marseille, France
ⁿ Hopital de la Conception, Marseille, France
^o Hopital de la Conception, Marseille, France
^p Hopital de la Conception, Marseille, France
^q Hopital de la Conception, Marseille, France
^r Hopital de la Conception, Marseille, France
^s Hopital Nord, France
^t Hopital Nord, France
^u Hopital Nord, France
^v Hopital Nord, France; Hopital Sainte Marguerite, France
^w Hopital Sainte Marguerite, France
^x Hopital Sainte Marguerite, France
^y Hopital Sainte Marguerite, France
^z Hopital Sainte Marguerite, France
^a Hopital Gui de Chauliac, Montpellier, France
^b Hopital Gui de Chauliac, Montpellier, France
^c Hopital Gui de Chauliac, Montpellier, France
^d Hopital Gui de Chauliac, Montpellier, France
^e Hopital Gui de Chauliac, Montpellier, France
^f Hopital Gui de Chauliac, Montpellier, France
^g Hopital Gui de Chauliac, Montpellier, France
^h Hopital Gui de Chauliac, Montpellier, France
ⁱ Hopital Gui de Chauliac, Montpellier, France
^j Hopital Jacques Monod, Montivilliers, France
^k Hotel-Dieu, Nantes, France
^l Hotel-Dieu, Nantes, France
^m Hotel-Dieu, Nantes, France
ⁿ Hotel-Dieu, Nantes, France
^o Hotel-Dieu, Nantes, France
^p Hotel-Dieu, Nantes, France
^q Hotel-Dieu, Nantes, France
^r Hotel-Dieu, Nantes, France
^s Hotel-Dieu, Nantes, France
^t Hotel-Dieu, Nantes, France
^u Hotel-Dieu, Nantes, France
^v Hotel-Dieu, Nantes, France
^w Hotel-Dieu, Nantes, France
^x Hotel-Dieu, Nantes, France
^y Hotel-Dieu, Nantes, France
^z Hotel-Dieu, Nantes, France
^a Hopital l'Archet, Nice, France
^b Hopital l'Archet, Nice, France
^c Hopital l'Archet, Nice, France
^d Hopital l'Archet, Nice, France
^e Hopital l'Archet, Nice, France
^f Hopital l'Archet, Nice, France
^g Hopital l'Archet, Nice, France
^h Hopital l'Archet, Nice, France
ⁱ Hopital l'Archet, Nice, France
^j Hopital l'Archet, Nice, France
^k Hopital l'Archet, Nice, France
^l Hopital l'Archet, Nice, France
^m Hopital l'Archet, Nice, France
ⁿ Hopital l'Archet, Nice, France
^o Hopital l'Archet, Nice, France
^p Hopital l'Archet, Nice, France
^q Hopital de la Source, Orleans, France
^r Hopital de la Source, Orleans, France
^s Hopital de la Source, Orleans, France
^t Hopital Porte Madeleine, France
^u Hopital Porte Madeleine, France
^v Hopital Bichat - Claude-Bernard, Paris, France
^w Hopital Bichat - Claude-Bernard, Paris, France
^x Hopital Bichat - Claude-Bernard, Paris, France
^y Hopital Bichat - Claude-Bernard, Paris, France
^z Hopital Bichat - Claude-Bernard, Paris, France
^a Hopital Bichat - Claude-Bernard, Paris, France
^b Hopital Bichat - Claude-Bernard, Paris, France
^c Hopital Bichat - Claude-Bernard, Paris, France
^d Hopital Bichat - Claude-Bernard, Paris, France
^e Hopital Bichat - Claude-Bernard, Paris, France
^f Hopital Bichat - Claude-Bernard, Paris, France
^g Hopital Bichat - Claude-Bernard, Paris, France
^h Hopital Bichat - Claude-Bernard, Paris, France
ⁱ Hopital Bichat - Claude-Bernard, Paris, France
^j Hopital Bichat - Claude-Bernard, Paris, France
^k Hopital Bichat - Claude-Bernard, Paris, France
^l Hopital Bichat - Claude-Bernard, Paris, France
^m Hopital Bichat - Claude-Bernard, Paris, France
ⁿ Hopital Bichat - Claude-Bernard, Paris, France
^o Hopital Bichat - Claude-Bernard, Paris, France
^p Hopital Bichat - Claude-Bernard, Paris, France
^q Hopital Bichat - Claude-Bernard, Paris, France
^r Hopital Bichat - Claude-Bernard, Paris, France
^s Hopital Cochin-Tarnier, France
^t Hopital Cochin-Tarnier, France
^u Hopital Cochin-Tarnier, France
^v Hopital Cochin-Tarnier, France
^w Hopital Cochin-Tarnier, France
^x Hopital Europeen Georges-Pompidou, France
^y Hopital Europeen Georges-Pompidou, France
^z Hopital Europeen Georges-Pompidou, France
^a Hopital Europeen Georges-Pompidou, France
^b Hopital Europeen Georges-Pompidou, France
^c Hopital Europeen Georges-Pompidou, France
^d Hopital Europeen Georges-Pompidou, France
^e Hopital Europeen Georges-Pompidou, France
^f Hopital Europeen Georges-Pompidou, France
^g Hopital Europeen Georges-Pompidou, France; Hopital Saint-Louis, France
^h Hopital Europeen Georges-Pompidou, France
ⁱ Hopital Europeen Georges-Pompidou, France
^j Hopital Lariboisiere, France
^k Hopital Lariboisiere, France
^l Hopital Lariboisiere, France
^m Hopital Lariboisiere, France
ⁿ Hopital Lariboisiere, France
^o Hopital Lariboisiere, France
^p Hopital Lariboisiere, France
^q Hopital Pitie-Salpetriere, France
^r Hopital Pitie-Salpetriere, France
^s Hopital Pitie-Salpetriere, France
^t Hopital Pitie-Salpetriere, France
^u Hopital Pitie-Salpetriere, France
^v Hopital Pitie-Salpetriere, France
^w Hopital Pitie-Salpetriere, France
^x Hopital Pitie-Salpetriere, France
^y Hopital Pitie-Salpetriere, France
^z Hopital Pitie-Salpetriere, France
^a Hopital Pitie-Salpetriere, France
^b Hopital Pitie-Salpetriere, France
^c Hopital Pitie-Salpetriere, France
^d Hopital Pitie-Salpetriere, France
^e Hopital Pitie-Salpetriere, France
^f Hopital Pitie-Salpetriere, France
^g Hopital Pitie-Salpetriere, France
^h Hopital Pitie-Salpetriere, France
ⁱ Hopital Pitie-Salpetriere, France
^j Hopital Saint-Antoine, France
^k Hopital Saint-Antoine, France
^l Hopital Saint-Antoine, France
^m Hopital Saint-Antoine, France
ⁿ Hopital Saint-Antoine, France
^o Hopital Saint-Antoine, France
^p Hopital Saint-Antoine, France
^q Hopital Saint-Antoine, France
^r Hopital Saint-Antoine, France
^s Hopital Saint-Antoine, France
^t Hopital Saint-Antoine, France
^u Hopital Saint-Antoine, France
^v Hopital Saint-Antoine, France
^w Hopital Saint-Antoine, France
^x Hopital Saint-Antoine, France
^y Hopital Saint-Antoine, France
^z Hopital Saint-Antoine, France
^a Hopital Saint-Antoine, France
^b Hopital Saint-Antoine, France
^c Hopital Saint-Antoine, France
^d Hopital Saint-Antoine, France
^e Hopital Saint-Antoine, France
^f Hopital Saint-Louis, France
^g Hopital Saint-Louis, France
^h Hopital Saint-Louis, France
ⁱ Hopital Saint-Louis, France
^j Hopital Saint-Louis, France
^k Hopital Saint-Louis, France
^l Hopital Saint-Louis, France
^m Hopital Saint-Louis, France
ⁿ Hopital Saint-Louis, France
^o Hopital Saint-Louis, France
^p Hopital Saint-Louis, France
^q Hopital Saint-Louis, France
^r Hopital Saint-Louis, France
^s Hopital Saint-Louis, France; Hotel-Dieu, France
^t Hopital Saint-Louis, France
^u Hopital Saint-Louis, France
^v Hopital Saint-Louis, France
^w Hopital Tenon, France
^x Hopital Tenon, France
^y Hopital Tenon, France
^z Hopital Tenon, France
^a Hopital Tenon, France
^b Hopital Tenon, France
^c Hopital Tenon, France
^d Hopital Tenon, France
^e Hopital Tenon, France
^f Hopital Tenon, France
^g Hotel-Dieu, France
^h Hotel-Dieu, France
ⁱ Hotel-Dieu, France
^j Hotel-Dieu, France
^k Hotel-Dieu, France
^l Hotel-Dieu, France
^m Hotel-Dieu, France
ⁿ Hopital Saint-Jean, Perpignan, France
^o Hopital Saint-Jean, Perpignan, France
^p Hopital Saint-Jean, Perpignan, France
^q Hopital Saint-Jean, Perpignan, France
^r Hopital Saint-Jean, Perpignan, France
^s Hopital Saint-Jean, Perpignan, France
^t Hopital Saint-Jean, Perpignan, France
^u CH Rene Dubos, Pontoise, France
^v Hopital Laennec, Quimper, France
^w Hopital de Pontchaillou, Rennes, France
^x Hopital de Pontchaillou, Rennes, France
^y Hopital de Pontchaillou, Rennes, France
^z Hopital de Pontchaillou, Rennes, France
^a Hopital de Pontchaillou, Rennes, France
^b Hopital Charles-Nicolle, Rouen, France
^c Hopital Charles-Nicolle, Rouen, France
^d Hopital Charles-Nicolle, Rouen, France
^e Hopital Charles-Nicolle, Rouen, France
^f Hopital Charles-Nicolle, Rouen, France
^g Hopital Charles-Nicolle, Rouen, France
^h Hopital Charles-Nicolle, Rouen, France
ⁱ Hopital Charles-Nicolle, Rouen, France
^j Hopital Charles-Nicolle, Rouen, France
^k Hopital Charles-Nicolle, Rouen, France
^l Hopital Charles-Nicolle, Rouen, France
^m Hopital Charles-Nicolle, Rouen, France
ⁿ C. H. Delafontaine, Saint-Denis, France
^o C. H. Delafontaine, Saint-Denis, France
^p C. H. Delafontaine, Saint-Denis, France
^q C. H. Delafontaine, Saint-Denis, France
^r CHU Nord, Saint-Etienne, France
^s CHU Nord, Saint-Etienne, France
^t CHU Nord, Saint-Etienne, France
^u CHU Nord, Saint-Etienne, France
^v CHU Nord, Saint-Etienne, France
^w CHU Nord, Saint-Etienne, France
^x Nouvel Hopital Civil, Strasbourg, France
^y Nouvel Hopital Civil, Strasbourg, France
^z Nouvel Hopital Civil, Strasbourg, France
^a Nouvel Hopital Civil, Strasbourg, France
^b Nouvel Hopital Civil, Strasbourg, France
^c Nouvel Hopital Civil, Strasbourg, France
^d Nouvel Hopital Civil, Strasbourg, France
^e Hopital Foch, Suresnes, France
^f Hopital Foch, Suresnes, France
^g CHI Chalucet, Toulon, France
^h CHI Chalucet, Toulon, France
ⁱ Hopital Sainte-Anne, France
^j Hopital Sainte-Anne, France
^k Hopital de la Grave, Toulouse, France
^l Hopital de la Grave, Toulouse, France
^m Hopital Purpan, France
ⁿ Hopital Purpan, France
^o Hopital Purpan, France
^p Hopital Purpan, France
^q Hopital Purpan, France
^r Hopital Purpan, France
^s Hopital Purpan, France
^t Hopital Purpan, France
^u Hopital Purpan, France
^v CH Gustave Dron, Tourcoing, France
^w CH Gustave Dron, Tourcoing, France
^x CH Gustave Dron, Tourcoing, France
^y CH Gustave Dron, Tourcoing, France
^z CH Gustave Dron, Tourcoing, France
^a CH Gustave Dron, Tourcoing, France
^b CH Gustave Dron, Tourcoing, France
^c CH Gustave Dron, Tourcoing, France
^d CH Gustave Dron, Tourcoing, France
^e CH Gustave Dron, Tourcoing, France
^f CHRU Bretonneau, Tours, France
^g CHRU Bretonneau, Tours, France
^h CHRU Bretonneau, Tours, France
ⁱ CHRU Bretonneau, Tours, France
^j CHU Brabois, Vandoeuvre-les-Nancy, France
^k CHU Brabois, Vandoeuvre-les-Nancy, France
^l CH Bretagne Atlantique, Vannes, France
^m CH Bretagne Atlantique, Vannes, France
ⁿ Hopital Paul-Brousse, Villejuif, France
^o Hopital Paul-Brousse, Villejuif, France
^p Hopital Paul-Brousse, Villejuif, France
^q Hopital Paul-Brousse, Villejuif, France
^r CHI de Villeneuve-Saint-Georges, France
^s CHI de Villeneuve-Saint-Georges, France
^t CHI de Villeneuve-Saint-Georges, France
^u [Affiliation not available]

Abstract

Objective: Although antiretroviral treatment (ART) no longer requires 100% adherence, voluntary treatment interruption (VTI) still may have a negative impact on virologic success. Previous studies have shown that posttraumatic stress disorder (PTSD) is more prevalent in HIV-infected patients than in the general population. However, no study has yet investigated the relationship between PTSD and VTI. We analyzed this relationship using data from a French national survey representative of HIV-infected adults followed up in hospitals. Methods: A total of 3,022 HIV-infected adults participated in the ANRS-VESPA2 survey (April 2011-January 2012) and answered a face-to-face questionnaire that included the Composite International Diagnostic Interview Short-Form to diagnose PTSD and assess sociobehavioral variables such as VTI. Multivariable logistic regression models were used to study the relationship between PTSD and VTI. Results: Among the 2,768 ART-treated participants with available data for both PTSD screening and ART interruption (study sample), prevalence of PTSD was 13.3%, and 7.2% of individuals reported VTI during the previous month. After adjustment for being a female Sub-Saharan African immigrant and reporting harmful alcohol consumption (Alcohol Use Disorders Identification Test score ≥ 8), lifetime PTSD was found to be independently associated with VTI (adjusted odds ratio [95% CI] = 1.64 [1.07-2.53], P = .025). Conclusions: PTSD is highly prevalent in HIV-infected patients followed up in French hospitals and is a significant predictor of VTI. PTSD is a psychiatric disorder that is still underdiagnosed and undertreated in many countries despite its negative consequences on health behaviors. As there is evidence of effective treatment for PTSD, HIV care providers need to be trained in screening for this disorder. © Copyright 2018 Physicians Postgraduate Press, Inc.

Author Keywords

[No Keywords available]

Index Keywords

immigrant HIV Infections Africa south of the Sahara Human immunodeficiency virus infection alcohol consumption France follow up human comorbidity middle aged statistics and numerical data controlled study Human immunodeficiency virus infected patient priority journal Anti-Retroviral Agents treatment interruption alcohol antiretrovirus agent Health Surveys Cross-Sectional Studies cross-sectional study migrant Humans male Emigrants and Immigrants female prediction questionnaire prevalence Article patient compliance major clinical study adult posttraumatic stress disorder sex factor Sex Factors antiretroviral therapy Stress Disorders, Post-Traumatic health survey

Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049477599&doi=10.4088%2fJCP.17m11659&partnerID=40&md5=fe3246b0085a421d31e45514af369bb6

DOI: 10.4088/JCP.17m11659

ISSN: 01606689

Original Language: English