BMC Public Health
Volume 19, Issue 1, 2019

Diagnostic pathways and delay among tuberculosis patients in Stockholm, Sweden: A retrospective observational study (Article) (Open Access)

Wikell A.* , Åberg H. , Shedrawy J. , Röhl I. , Jonsson J. , Berggren I. , Buxbaum C. , Lönnroth K. , Bruchfeld J.
  • a Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden
  • b Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden
  • c Department of Public Health Sciences, Karolinska Institutet, Stockholm, 171 77, Sweden
  • d Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden
  • e Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden, Public Health Agency of Sweden, Solna, 171 65, Sweden
  • f Department of Communicable Disease Control and Prevention, Stockholm County Council, Stockholm, 118 91, Sweden
  • g Department of Pediatrics, Karolinska University Hospital Huddinge, Stockholm, 141 86, Sweden
  • h Department of Public Health Sciences, Karolinska Institutet, Stockholm, 171 77, Sweden, Centre for Epidemiology and Community Medicine, Stockholm County, Stockholm, 104 31, Sweden
  • i Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden, Department of Infectious Diseases, Karolinska University Hospital Solna, Stockholm, 171 76, Sweden

Abstract

Background: Asylum seekers in Sweden are offered tuberculosis (TB) screening at a voluntary post-arrival health examination. The role of this screening in improving the TB diagnostic pathway has not been previously evaluated. The aim of this study was to determine diagnostic pathways for active TB cases and compare diagnostic delays between different pathways. Methods: Retrospective review of medical records of patients reported with active TB in Stockholm in 2015, using a structured and pre-coded form. Results: Seventy-one percent of patients actively sought health care due to symptoms. As for source of referral to TB specialist clinic, 15% came from screening of eligible migrants, of whom the majority were asymptomatic. Among asylum seekers, 69% were identified through screening at a health examination (HE). The main sources of referral to TB clinics were emergency departments (27%) and primary health care centers (20%). Median health care provider delay was significantly longer in patients identified through migrant screening in health examination. Conclusions: Screening at a health examination was the main pathway of active TB detection among mainly asymptomatic and non-contagious asylum seekers but contributed modestly to total overall TB case detection. In these patients TB was diagnosed early in a non-contagious phase of the disease. Further research is required to assess the effectiveness and cost-effectiveness of HE TB screening as well as inclusion of other groups of migrants from high incidence countries in the screening program in terms of impact on delay, transmission and treatment outcomes. © 2019 The Author(s).

Author Keywords

Screening Asylum seekers tuberculosis Health examination Diagnostic delay

Index Keywords

refugee mass screening human delayed diagnosis Refugees middle aged statistics and numerical data Aged Young Adult Sweden Humans Medical Records Adolescent Infant, Newborn male preschool child Aged, 80 and over tuberculosis very elderly Infant Child, Preschool medical record newborn female Retrospective Studies adult retrospective study Child
Link
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061144834&doi=10.1186%2fs12889-019-6462-5&partnerID=40&md5=6d6226fcf7bfd4ed0f963c217f73a740
DOI: 10.1186/s12889-019-6462-5
ISSN: 14712458
Original Language: English